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Phospho-AKT1(Ser473)Monoclonal Antibody E-AB-51038

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特徴

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  • アズワン株式会社 輸入試薬グループ
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  • 主な研究分野例:Cancer, Epigenetics and Nuclear Signaling, Metabolism, Signal Transduction
  • 背景:The serine-threonine protein kinase AKT1 is catalytically inactive in serum-starved primary and immortalized fibroblasts. AKT1 and the related AKT2 are activated by platelet-derived growth factor. The activation is rapid and specific, and it is abrogated by mutations in the pleckstrin homology domain of AKT1. It was shown that the activation occurs through phosphatidylinositol 3-kinase. In the developing nervous system AKT is a critical mediator of growth factor-induced neuronal survival. Survival factors can suppress apoptosis in a transcription-independent manner by activating the serine/threonine kinase AKT1, which then phosphorylates and inactivates components of the apoptotic machinery.

共通仕様

  • 研究分野:分子生物学
アズワン品番 商品名 型番 入り数 標準価格
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備考 数量
89-7913-64 Phospho-AKT1 (Ser473) Monoclonal Antibody 20uL  E-AB-51038
E-AB-51038
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1個 32,000円

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89-7913-65 Phospho-AKT1 (Ser473) Monoclonal Antibody 60uL  E-AB-51038
E-AB-51038
  • 冷凍
1個 39,000円

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89-7913-66 Phospho-AKT1 (Ser473) Monoclonal Antibody 120uL  E-AB-51038
E-AB-51038
  • 冷凍
1個 52,000円

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89-7913-67 Phospho-AKT1 (Ser473) Monoclonal Antibody 200uL  E-AB-51038
E-AB-51038
  • 冷凍
1個 73,000円

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