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PDGFB Polyclonal Antibody E-AB-40267

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特徴

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  • 主な研究分野例:Cancer, Cardiovascular, Metabolism, Developmental Biology, Signal Transduction
  • 背景:The protein encoded by this gene is a member of the platelet-derived growth factor family. The four members of this family are mitogenic factors for cells of mesenchymal origin and are characterized by a motif of eight cysteines. This gene product can exist either as a homodimer (PDGF-BB) or as a heterodimer with the platelet-derived growth factor alpha polypeptide (PDGF-AB), where the dimers are connected by disulfide bonds. Mutations in this gene are associated with meningioma. Reciprocal translocations between chromosomes 22 and 7, at sites where this gene and that for COL1A1 are located, are associated with a particular type of skin tumor called dermatofibrosarcoma protuberans resulting from unregulated expression of growth factor. Two alternatively spliced transcript variants encoding different isoforms have been identified for this gene.

共通仕様

  • 研究分野:分子生物学
アズワン品番 商品名 型番 入り数 標準価格
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備考 数量
89-7908-63 PDGFB Polyclonal Antibody 20uL  E-AB-40267
E-AB-40267
  • 冷凍
1個 30,000円

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89-7908-64 PDGFB Polyclonal Antibody 60uL  E-AB-40267
E-AB-40267
  • 冷凍
1個 38,000円

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89-7908-65 PDGFB Polyclonal Antibody 120uL  E-AB-40267
E-AB-40267
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1個 51,000円

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89-7908-66 PDGFB Polyclonal Antibody 200uL  E-AB-40267
E-AB-40267
  • 冷凍
1個 68,000円

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