89-8147-05 ［取扱停止］Recombinant 2019-nCoV Papain-like Protease Protein (His Tag) 1mg PKSR030511
[Elabscience]
特徴
- 背景：The coronaviral proteases, papain-like protease (PLpro) and 3C-like protease (3CLpro), are attractive antiviral drug targets because they are essential for coronaviral replication. PLpro has the additional function of stripping ubiquitin and ISG15 from host-cell proteins to aid coronaviruses in their evasion of the host innate immune responses. Targeting PLpro with antiviral drugs may have an advantage in not only inhibiting viral replication but also inhibiting the dysregulation of signaling cascades in infected cells that may lead to cell death in surrounding, uninfected cells.
仕様
- サイズ：1mg
- 種由来：virus
- 発現宿主：E.coli
- 純度：> 90 % as determined by reducing SDS-PAGE.
- 遺伝子構造：A DNA sequence encoding the SARS-CoV-2 (2019-nCoV) papain-like protease (YP_009725299.1) (Glu1564-Val1880) was expressed with a polyhistidine tag at the N-terminus.
- 別名（遺伝子名）：Papain-like Protease; PLpro; PL-PRO; pp1a; Replicase polyprotein 1a
- アミノ酸配列：Glu1564-Val1880
- タグ種類：N-6His
- アクセッションＮｏ．：YP_009725299.1
- エンドトキシン濃度：< 1.0 EU per µg as determined by the LAL method.
- 分子量：36.79 kDa
- 組成：Lyophilized from sterile 20 mM Tris 500mM NaCl, pH 7.4.
- 保存条件：Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
- メーカーマニュアルリンク：https://www.elabscience.com//viewpdf-376357-Elabscience-PKSR030511.pdf
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商品のバリエーション （サイズ違い・スペック違い・オプション品など）
| 商品イメージ | アズワン品番 商品名 |
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89-8147-05
Recombinant 2019-nCoV Papain-like Protease Protein (His Tag) 1mg
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89-8147-04
Recombinant 2019-nCoV Papain-like Protease Protein (His Tag) 100ug
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