89-8141-45　［取扱停止］CK-20 Monoclonal Antibody 60uL　E-AB-71055

特徴

• 主な研究分野例：Cancer, Signal Transduction
• 背景：KRT20 is a member of the keratin family. The keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells and are subdivided into cytokeratins and hair keratins. The type I cytokeratins consist of acidic proteins which are arranged in pairs of heterotypic keratin chains. This cytokeratin is a major cellular protein of mature enterocytes and goblet cells and is specifically expressed in the gastric and intestinal mucosa. Diseases associated with KRT20 includeMerkel Cell CarcinomaandCystic Teratoma. Cytokeratin 20 (CK20) has a molecular weight of 46 kDa, which is the main marker of gastrointestinal epithelial, urethral epithelial and Merkel cells. CK20 is mainly used for diagnosis of gastrointestinal adenocarcinoma, ovarian mucinous tumors and Merkel cell carcinoma. There is no expression of CK20 in squamous cell carcinoma, breast cancer, lung cancer, endometrial cancer and ovarian non-mucinous tumors.

仕様

• サイズ：60uL
• 抗体タイプ：Monoclonal Antibody
• アプリケーション：IHC-p
• 交差性：Human
• 宿主：Mouse
• アイソタイプ：IgG
• 濃度：1 mg/mL
• 抗原：Full length protein from eukaryotic expression system.
• 緩衝液：PBS with 0.02% sodium azide and 50% glycerol pH 7.4.
• 精製方法：Affinity purification
• 希釈倍率：IHC 1:100-1:200
• 標識：Unconjugated
• クローナリティ：Monoclonal
• メーカーマニュアルリンク：https://www.elabscience.com/viewpdf-52409-Elabscience-E-AB-71055.pdf
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