特徴
- 主な研究分野例：Cancer, Signal Transduction
- 背景：KRT19 is a member of the keratin family. The keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells and are subdivided into cytokeratins and hair keratins. The type I cytokeratins consist of acidic proteins which are arranged in pairs of heterotypic keratin chains. Unlike its related family members, this smallest known acidic cytokeratin is not paired with a basic cytokeratin in epithelial cells. It is specifically expressed in the periderm, the transiently superficial layer that envelopes the developing epidermis. Diseases associated with KRT19 include Anal Canal Adenocarcinoma and Thyroid Cancer. Among its related pathways are Signaling mediated by p38-alpha and p38-beta and Embryonic and Induced Pluripotent Stem Cell Differentiation Pathways and Lineage-specific Markers.This antibody reacts with the 40 kDa protein corresponding to cytokeratin 19 and labels many types of simple and non-keratinizing epithelia, including ductal and glandular epithelia. The antibody is a useful aid for classification of tumors of epithelial origin.
仕様
- サイズ：60uL
- 抗体タイプ：Monoclonal Antibody
- アプリケーション：IHC-p
- 交差性：Human
- 宿主：Mouse
- アイソタイプ：IgG
- 濃度：1 mg/mL
- 抗原：Full length protein from eukaryotic expression system.
- 緩衝液：PBS with 0.02% sodium azide and 50% glycerol pH 7.4.
- 精製方法：Affinity purification
- 希釈倍率：IHC 1:100-1:200
- 標識：Unconjugated
- クローナリティ：Monoclonal
- メーカーマニュアルリンク：https://www.elabscience.com/viewpdf-52408-Elabscience-E-AB-71054.pdf
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商品のバリエーション （サイズ違い・スペック違い・オプション品など）
| 商品イメージ | アズワン品番 商品名 |
|---|---|
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89-8141-42
CK-19 Monoclonal Antibody 120uL
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89-8141-41
CK-19 Monoclonal Antibody 60uL
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89-8141-40
CK-19 Monoclonal Antibody 20uL
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89-8141-43
CK-19 Monoclonal Antibody 200uL
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