89-8137-22　MTOR Polyclonal Antibody 60uL　E-AB-70304

特徴

• 主な研究分野例：Cancer, Cell Biology, Cardiovascular, Epigenetics and Nuclear Signaling, Metabolism
• 背景：MTOR, also named as FRAP1, FRAP, FRAP2 and RAPT1, belongs to the PI3/PI4-kinase family. MTOR is a Ser/Thr protein kinase that functions as an ATP and amino acid sensor to balance nutrient availability and cell growth. MTOR is Kinase subunit of both mTORC1 and mTORC2, which regulate cell growth and survival in response to nutrient and hormonal signals. mTORC1 is activated in response to growth factors or amino-acids. mTORC2 is also activated by growth factors, but seems to be nutrient-insensitive. mTORC2 seems to function upstream of Rho GTPases to regulate the actin cytoskeleton, probably by activating one or more Rho-type guanine nucleotide exchange factors. mTORC2 promotes the serum-induced formation of stress-fibers or F-actin. The antibody is specific to MTOR.

仕様

• サイズ：60uL
• 抗体タイプ：Polyclonal Antibody
• アプリケーション：WB
• 交差性：Human,Mouse,Rat
• 宿主：Rabbit
• アイソタイプ：IgG
• 濃度：0.8 mg/mL
• 抗原：Recombinant protein corresponding to Mouse mTOR
• 緩衝液：PBS with 0.02% sodium azide, 1% BSA and 50% glycerol, pH7.4
• 精製方法：Affinity purification
• 希釈倍率：WB 1:500-1:2000
• 標識：Unconjugated
• クローナリティ：Polyclonal
• メーカーマニュアルリンク：https://www.elabscience.com/viewpdf-51884-Elabscience-E-AB-70304.pdf
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