89-8136-16　RBFOX3 Polyclonal Antibody 60uL　E-AB-70267

特徴

• 主な研究分野例：Cancer, Epigenetics and Nuclear Signaling, Neuroscience, Tags and Cell Markers
• 背景：Immunoprecipitation and mass spectrometry of the two major NeuN species at 45–50 kDa identified both as the RNA binding protein Rbfox3 (a member of the Fox family of alternative splicing factors), confirming and extending the identification of the 45 kDa band as Rbfox3. Mapping of the anti-NeuN reactive epitopes in both R3hdm2 and Rbfox3 reveals a common proline- and glutamine-rich domain that lies at the N-terminus of the Rbfox3 protein. Nuclear Rbfox3 isoforms can also enhance the inclusion of cryptic exons in the Rbfox2 mRNA, resulting in nonsense-mediated decay of the message, thereby contributing to the negative regulation of Rbfox2 by Rbfox3 through a novel mechanism.

仕様

• サイズ：60uL
• 抗体タイプ：Polyclonal Antibody
• アプリケーション：WB,IHC
• 交差性：Mouse,Rat
• 宿主：Rabbit
• アイソタイプ：IgG
• 濃度：1 mg/mL
• 抗原：KLH conjugated Synthetic peptide corresponding to NeuN
• 緩衝液：PBS with 0.02% sodium azide, 1% BSA and 50% glycerol, pH7.4
• 精製方法：Affinity purification
• 希釈倍率：WB 1:500-1:2000, IHC 1:300-1:800
• 標識：Unconjugated
• クローナリティ：Polyclonal
• メーカーマニュアルリンク：https://www.elabscience.com/viewpdf-51847-Elabscience-E-AB-70267.pdf
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