89-8135-64　E-Cadherin Monoclonal Antibody 60uL　E-AB-70249

特徴

• 主な研究分野例：Cancer, Developmental Biology, Signal Transduction
• 背景：This gene is a classical cadherin from the cadherin superfamily. The encoded protein is a calcium dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Mutations in this gene are correlated with gastric, breast, colorectal, thyroid and ovarian cancer. Loss of function is thought to contribute to progression in cancer by increasing proliferation, invasion, and/or metastasis. The ectodomain of this protein mediates bacterial adhesion to mammalian cells and the cytoplasmic domain is required for internalization. Identified transcript variants arise from mutation at consensus splice sites.

仕様

• サイズ：60uL
• 抗体タイプ：Monoclonal Antibody
• アプリケーション：IHC
• 交差性：Mouse,Rat
• 宿主：Mouse
• アイソタイプ：IgG
• 濃度：1.6 mg/mL
• 抗原：Recombinant protein corresponding to MouseE-cadherin
• 緩衝液：PBS with 0.02% sodium azide, 1% BSA and 50% glycerol, pH7.4
• 精製方法：Affinity purification
• 希釈倍率：IHC 1:200-1:800
• 標識：Unconjugated
• クローナリティ：Monoclonal
• メーカーマニュアルリンク：https://www.elabscience.com/viewpdf-51829-Elabscience-E-AB-70249.pdf
• この商品は法規制を確認しておりません。（法規制によって販売できない場合もございます）

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