特徴
- 主な研究分野例：Cancer, Immunology, Microbiology, Signal Transduction
- 背景：Elastases form a subfamily of serine proteases that hydrolyze many proteins in addition to elastin. Humans have six elastase genes which encode structurally similar proteins. The encoded preproprotein is proteolytically processed to generate the active protease. Following activation, this protease hydrolyzes proteins within specialized neutrophil lysosomes, called azurophil granules, as well as proteins of the extracellular matrix. The enzyme may play a role in degenerative and inflammatory diseases through proteolysis of collagen-IV and elastin. This protein also degrades the outer membrane protein A (OmpA) of E. coli as well as the virulence factors of such bacteria as Shigella, Salmonella and Yersinia. Mutations in this gene are associated with cyclic neutropenia and severe congenital neutropenia (SCN). This gene is present in a gene cluster on chromosome 19.
仕様
- サイズ：200uL
- 抗体タイプ：Polyclonal Antibody
- アプリケーション：WB
- 交差性：Human,Mouse
- 宿主：Rabbit
- アイソタイプ：IgG
- 濃度：1 mg/mL
- 抗原：Recombinant Protein of human ELANE
- 緩衝液：PBS with 0.02% sodium azide and 50% glycerol pH 7.4.
- 精製方法：Affinity purification
- 希釈倍率：WB1:500 - 1:2000
- 標識：Unconjugated
- クローナリティ：Polyclonal
- メーカーマニュアルリンク：https://www.elabscience.com/viewpdf-46132-Elabscience-E-AB-64417.pdf
- この商品は法規制を確認しておりません。（法規制によって販売できない場合もございます）
- 【試薬に関するお問合せ】
- アズワン株式会社 試薬・プロセス材料グループ
- TEL：06-6447-8641
- FAX：06-6447-8642
- E-mail：[email protected]
商品のバリエーション （サイズ違い・スペック違い・オプション品など）
| 商品イメージ | アズワン品番 商品名 |
|---|---|
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89-8092-31
ELANE Polyclonal Antibody 60uL
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89-8092-32
ELANE Polyclonal Antibody 120uL
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89-8092-33
ELANE Polyclonal Antibody 200uL
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掲載カタログ情報
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