特徴
- 主な研究分野例：Cancer, Cardiovascular, Neuroscience
- 背景：The protein encoded by this gene is a member of the signal-regulatory-protein (SIRP) family, and also belongs to the immunoglobulin superfamily. SIRP family members are receptor-type transmembrane glycoproteins known to be involved in the negative regulation of receptor tyrosine kinase-coupled signaling processes. This protein can be phosphorylated by tyrosine kinases. The phospho-tyrosine residues of this PTP have been shown to recruit SH2 domain containing tyrosine phosphatases (PTP), and serve as substrates of PTPs. This protein was found to participate in signal transduction mediated by various growth factor receptors. CD47 has been demonstrated to be a ligand for this receptor protein. This gene and its product share very high similarity with several other members of the SIRP family. These related genes are located in close proximity to each other on chromosome 20p13. Multiple alternatively spliced transcript variants have been determined for this gene.
仕様
- サイズ：60uL
- 抗体タイプ：Polyclonal Antibody
- アプリケーション：WB
- 交差性：Human,Mouse,Rat
- 宿主：Rabbit
- アイソタイプ：IgG
- 濃度：1 mg/mL
- 抗原：Recombinant protein of human SIRPA
- 緩衝液：PBS with 0.02% sodium azide and 50% glycerol pH 7.4.
- 精製方法：Affinity purification
- 希釈倍率：WB1:200 - 1:2000
- 標識：Unconjugated
- クローナリティ：Polyclonal
- メーカーマニュアルリンク：https://www.elabscience.com/viewpdf-50310-Elabscience-E-AB-63918.pdf
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- 【試薬に関するお問合せ】
- アズワン株式会社 試薬・プロセス材料グループ
- TEL：06-6447-8641
- FAX：06-6447-8642
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商品のバリエーション （サイズ違い・スペック違い・オプション品など）
| 商品イメージ | アズワン品番 商品名 |
|---|---|
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89-8077-52
SIRPA Polyclonal Antibody 60uL
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89-8077-53
SIRPA Polyclonal Antibody 120uL
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89-8077-54
SIRPA Polyclonal Antibody 200uL
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掲載カタログ情報
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