特徴
- 主な研究分野例:Cancer, Cell Biology, Epigenetics and Nuclear Signaling
- 背景:This gene encodes a member of the argonaute family of proteins, which associate with small RNAs and have important roles in RNA interference (RNAi) and RNA silencing. This protein binds to microRNAs (miRNAs) or small interfering RNAs (siRNAs) and represses translation of mRNAs that are complementary to them. It is also involved in transcriptional gene silencing (TGS) of promoter regions that are complementary to bound short antigene RNAs (agRNAs), as well as in the degradation of miRNA-bound mRNA targets. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. A recent study showed this gene to be an authentic stop codon readthrough target, and that its mRNA could give rise to an additional C-terminally extended isoform by use of an alternative in-frame translation termination codon.
仕様
- サイズ:200uL
- 抗体タイプ:Polyclonal Antibody
- アプリケーション:WB
- 交差性:Human,Mouse
- 宿主:Rabbit
- アイソタイプ:IgG
- 濃度:1 mg/mL
- 抗原:Recombinant protein of human AGO1
- 緩衝液:PBS with 0.02% sodium azide and 50% glycerol pH 7.4.
- 精製方法:Affinity purification
- 希釈倍率:WB 1:500 - 1:1000
- 標識:Unconjugated
- クローナリティ:Polyclonal
- メーカーマニュアルリンク:https://www.elabscience.com/viewpdf-48621-Elabscience-E-AB-63834.pdf
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- アズワン株式会社 試薬・プロセス材料グループ
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商品のバリエーション (サイズ違い・スペック違い・オプション品など)
| 商品イメージ | アズワン品番 商品名 |
|---|---|
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89-8074-97
AGO1 Polyclonal Antibody 60uL
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89-8074-98
AGO1 Polyclonal Antibody 120uL
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89-8074-99
AGO1 Polyclonal Antibody 200uL
|
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掲載カタログ情報
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