特徴
- 主な研究分野例:Epigenetics and Nuclear Signaling
- 背景:The protein encoded by this gene is a cyclin-dependent kinase 2 (CDK2) -associated protein which is thought to negatively regulate CDK2 activity by sequestering monomeric CDK2, and targeting CDK2 for proteolysis. This protein was found to also interact with DNA polymerase alpha/primase and mediate the phosphorylation of the large p180 subunit, which suggests a regulatory role in DNA replication during the S-phase of the cell cycle. This protein also forms a core subunit of the nucleosome remodeling and histone deacetylation (NURD) complex that epigenetically regulates embryonic stem cell differentiation. This gene thus plays a role in both cell-cycle and epigenetic regulation. Alternative splicing results in multiple transcript variants encoding distinct isoforms.
仕様
- サイズ:120uL
- 抗体タイプ:Polyclonal Antibody
- アプリケーション:WB
- 交差性:Human
- 宿主:Rabbit
- アイソタイプ:IgG
- 濃度:1 mg/mL
- 抗原:Recombinant protein of human CDK2AP1
- 緩衝液:PBS with 0.02% sodium azide and 50% glycerol pH 7.4.
- 精製方法:Affinity purification
- 希釈倍率:WB1:500 - 1:2000
- 標識:Unconjugated
- クローナリティ:Polyclonal
- メーカーマニュアルリンク:https://www.elabscience.com/viewpdf-48043-Elabscience-E-AB-63780.pdf
- この商品は法規制を確認しておりません。(法規制によって販売できない場合もございます)
- 【試薬に関するお問合せ】
- アズワン株式会社 試薬・プロセス材料グループ
- TEL:06-6447-8641
- FAX:06-6447-8642
- E-mail:[email protected]
商品のバリエーション (サイズ違い・スペック違い・オプション品など)
| 商品イメージ | アズワン品番 商品名 |
|---|---|
|
89-8073-36
DOC1 Polyclonal Antibody 200uL
|
|
|
89-8073-35
DOC1 Polyclonal Antibody 120uL
|
|
|
89-8073-34
DOC1 Polyclonal Antibody 60uL
|
よくあるご質問(FAQ)
掲載カタログ情報
| 掲載カタログ名 | 掲載ページ |
|---|





