89-7981-76　［取扱停止］VDR Polyclonal Antibody 60uL　E-AB-60676

特徴

• 主な研究分野例：Cancer, Epigenetics and Nuclear Signaling, Signal Transduction
• 背景：This gene encodes the nuclear hormone receptor for vitamin D3. This receptor also functions as a receptor for the secondary bile acid lithocholic acid. The receptor belongs to the family of trans-acting transcriptional regulatory factors and shows sequence similarity to the steroid and thyroid hormone receptors. Downstream targets of this nuclear hormone receptor are principally involved in mineral metabolism though the receptor regulates a variety of other metabolic pathways, such as those involved in the immune response and cancer. Mutations in this gene are associated with type II vitamin D-resistant rickets. A single nucleotide polymorphism in the initiation codon results in an alternate translation start site three codons downstream. Alternative splicing results in multiple transcript variants encoding different proteins.

仕様

• サイズ：60uL
• 抗体タイプ：Polyclonal Antibody
• アプリケーション：WB
• 交差性：Human,Mouse,Rat
• 宿主：Rabbit
• アイソタイプ：IgG
• 濃度：1 mg/mL
• 抗原：Recombinant protein of human VDR
• 緩衝液：PBS with 0.02% sodium azide and 50% glycerol pH 7.4.
• 精製方法：Affinity purification
• 希釈倍率：WB 1:500 - 1:2000
• 標識：Unconjugated
• クローナリティ：Polyclonal
• メーカーマニュアルリンク：https://www.elabscience.com/viewpdf-47574-Elabscience-E-AB-60676.pdf
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