特徴
- 主な研究分野例:Cancer, Cardiovascular, Immunology, Neuroscience, Signal Transduction, Stem Cells
- 背景:The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitosis, and oncogenic transformation. This PTP contains an extracellular domain, a single transmembrane segment and two tandem intracytoplasmic catalytic domains, and thus is classified as a receptor type PTP. This PTP has been shown to be an essential regulator of T- and B-cell antigen receptor signaling. It functions through either direct interaction with components of the antigen receptor complexes, or by activating various Src family kinases required for the antigen receptor signaling. This PTP also suppresses JAK kinases, and thus functions as a regulator of cytokine receptor signaling. Alternatively spliced transcripts variants of this gene, which encode distinct isoforms, have been reported.
仕様
- サイズ:60uL
- 抗体タイプ:Polyclonal Antibody
- アプリケーション:WB,IHC
- 交差性:Human,Mouse,Rat
- 宿主:Rabbit
- アイソタイプ:IgG
- 濃度:1 mg/mL
- 抗原:A synthetic peptide of human PTPRC
- 緩衝液:PBS with 0.02% sodium azide and 50% glycerol pH 7.4.
- 精製方法:Affinity purification
- 希釈倍率:WB 1:500 - 1:2000 IHC 1:50 - 1:200
- 標識:Unconjugated
- クローナリティ:Polyclonal
- メーカーマニュアルリンク:https://www.elabscience.com/viewpdf-47516-Elabscience-E-AB-60618.pdf
- この商品は法規制を確認しておりません。(法規制によって販売できない場合もございます)
- 【試薬に関するお問合せ】
- アズワン株式会社 試薬・プロセス材料グループ
- TEL:06-6447-8641
- FAX:06-6447-8642
- E-mail:[email protected]
商品のバリエーション (サイズ違い・スペック違い・オプション品など)
| 商品イメージ | アズワン品番 商品名 |
|---|---|
|
89-7980-08
CD45 Polyclonal Antibody 120uL
|
|
|
89-7980-09
CD45 Polyclonal Antibody 200uL
|
|
|
89-7980-07
CD45 Polyclonal Antibody 60uL
|
よくあるご質問(FAQ)
掲載カタログ情報
| 掲載カタログ名 | 掲載ページ |
|---|





