89-7977-86　［取扱停止］IPO5 Polyclonal Antibody 120uL　E-AB-60539

特徴

• 主な研究分野例：Cancer, Epigenetics and Nuclear Signaling, Signal Transduction
• 背景：Nucleocytoplasmic transport, a signal- and energy-dependent process, takes place through nuclear pore complexes embedded in the nuclear envelope. The import of proteins containing a nuclear localization signal (NLS) requires the NLS import receptor, a heterodimer of importin alpha and beta subunits also known as karyopherins. Importin alpha binds the NLS-containing cargo in the cytoplasm and importin beta docks the complex at the cytoplasmic side of the nuclear pore complex. In the presence of nucleoside triphosphates and the small GTP binding protein Ran, the complex moves into the nuclear pore complex and the importin subunits dissociate. Importin alpha enters the nucleoplasm with its passenger protein and importin beta remains at the pore. Interactions between importin beta and the FG repeats of nucleoporins are essential in translocation through the pore complex. The protein encoded by this gene is a member of the importin beta family.

仕様

• サイズ：120uL
• 抗体タイプ：Polyclonal Antibody
• アプリケーション：WB,IF
• 交差性：Human,Mouse
• 宿主：Rabbit
• アイソタイプ：IgG
• 濃度：1 mg/mL
• 抗原：Recombinant protein of human IPO5
• 緩衝液：PBS with 0.02% sodium azide and 50% glycerol pH 7.4.
• 精製方法：Affinity purification
• 希釈倍率：WB1:500 - 1:2000 IF1:50 - 1:200
• 標識：Unconjugated
• クローナリティ：Polyclonal
• メーカーマニュアルリンク：https://www.elabscience.com/viewpdf-47425-Elabscience-E-AB-60539.pdf
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