特徴
- 主な研究分野例：Signal Transduction
- 背景：The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance. This gene is located 7 kb telomeric to gene family member ABCB2. The protein encoded by this gene is involved in antigen presentation. This protein forms a heterodimer with ABCB2 in order to transport peptides from the cytoplasm to the endoplasmic reticulum. Mutations in this gene may be associated with ankylosing spondylitis, insulin-dependent diabetes mellitus, and celiac disease. Alternative splicing of this gene produces products which differ in peptide selectivity and level of restoration of surface expression of MHC class I molecules.
仕様
- サイズ：60uL
- 抗体タイプ：Polyclonal Antibody
- アプリケーション：WB,IF
- 交差性：Human,Mouse,Rat
- 宿主：Rabbit
- アイソタイプ：IgG
- 濃度：1 mg/mL
- 抗原：Recombinant protein of human TAP2
- 緩衝液：PBS with 0.02% sodium azide and 50% glycerol pH 7.4.
- 精製方法：Affinity purification
- 希釈倍率：WB 1:500 - 1:2000 IF 1:50 - 1:200
- 標識：Unconjugated
- クローナリティ：Polyclonal
- メーカーマニュアルリンク：https://www.elabscience.com/viewpdf-47197-Elabscience-E-AB-60369.pdf
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- 【試薬に関するお問合せ】
- アズワン株式会社 試薬・プロセス材料グループ
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- E-mail：[email protected]
商品のバリエーション （サイズ違い・スペック違い・オプション品など）
| 商品イメージ | アズワン品番 商品名 |
|---|---|
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89-7972-90
TAP2 Polyclonal Antibody 200uL
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89-7972-89
TAP2 Polyclonal Antibody 120uL
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89-7972-88
TAP2 Polyclonal Antibody 60uL
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掲載カタログ情報
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