89-7954-65　ERBB2 Polyclonal Antibody 20uL　E-AB-53244

特徴

• 主な研究分野例：Cancer, Immunology, Signal Transduction, Tags and Cell Markers
• 背景：HER2,also known as ErbB2 and Neu,is a 185-kDa transmembrane glycoprotein that is a member of the epidermal growth factor (EGF) receptor family of receptor tyrosine kinases. It has no ligand binding domain of its own and therefore cannot bind growth factors. However,it does bind tightly to other ligand-bound EGF receptor family members to form a heterodimer,stabilizing ligand binding and enhancing kinase-mediated activation of downstream signalling pathways,such as those involving mitogen-activated protein kinase and phosphatidylinositol-3 kinase. Amplification and/or overexpression of HER2 have been reported in numerous cancers,including breast and ovarian tumors. HER2 is a therapeutic target for the treatment of breast cancer and other carcinomas.

仕様

• サイズ：20uL
• 抗体タイプ：Polyclonal Antibody
• アプリケーション：IHC,ELISA
• 交差性：Human
• 宿主：Rabbit
• アイソタイプ：IgG
• 濃度：1.68 mg/mL
• 抗原：Synthetic peptide of human ERBB2
• 緩衝液：PBS with 0.05% NaN3 and 40% Glycerol,pH7.4
• 精製方法：Antigen affinity purification
• 希釈倍率：IHC 1:50-1:100, ELISA 1:5000-1:10000
• 標識：Unconjugated
• クローナリティ：Polyclonal
• メーカーマニュアルリンク：https://www.elabscience.com/viewpdf-271639-Elabscience-E-AB-53244.pdf
• この商品は法規制を確認しておりません。（法規制によって販売できない場合もございます）

• 【試薬に関するお問合せ】
• アズワン株式会社 試薬・プロセス材料グループ
• TEL：06-6447-8641
• FAX：06-6447-8642
• E-mail：[email protected]