特徴
- 主な研究分野例:Cancer, Metabolism, Immunology, Signal Transduction
- 背景:This gene encodes an essential regulator of mitochondrial Ca2+ uptake under basal conditions. The encoded protein interacts with the mitochondrial calcium uniporter, a mitochondrial inner membrane Ca2+ channel, and is essential in preventing mitochondrial Ca2+ overload, which can cause excessive production of reactive oxygen species and cell stress. Alternatively spliced transcript variants encoding different isoforms have been described.MICU1 (Mitochondrial Calcium Uptake 1) is a Protein Coding gene. Diseases associated with MICU1 include Myopathy With Extrapyramidal Signs and Fish Allergy. Among its related pathways are Ca, cAMP and Lipid Signaling. GO annotations related to this gene include calcium ion binding and protein heterodimerization activity. An important paralog of this gene is MICU3.
仕様
- サイズ:120uL
- 抗体タイプ:Polyclonal Antibody
- アプリケーション:IHC,ELISA
- 交差性:Human, Mouse, Rat
- 宿主:Rabbit
- アイソタイプ:IgG
- 濃度:0.6 mg/mL
- 抗原:Fusion protein of human MICU1
- 緩衝液:PBS with 0.05% NaN3 and 40% Glycerol,pH7.4
- 精製方法:Antigen affinity purification
- 希釈倍率:IHC 1:30-1:150, ELISA 1:5000-1:10000
- 標識:Unconjugated
- クローナリティ:Polyclonal
- メーカーマニュアルリンク:https://www.elabscience.com/viewpdf-270914-Elabscience-E-AB-52519.pdf
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- 【試薬に関するお問合せ】
- アズワン株式会社 試薬・プロセス材料グループ
- TEL:06-6447-8641
- FAX:06-6447-8642
- E-mail:[email protected]
商品のバリエーション (サイズ違い・スペック違い・オプション品など)
| 商品イメージ | アズワン品番 商品名 |
|---|---|
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89-7927-76
MICU1 Polyclonal Antibody 120uL
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89-7927-75
MICU1 Polyclonal Antibody 60uL
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89-7927-77
MICU1 Polyclonal Antibody 200uL
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89-7927-74
MICU1 Polyclonal Antibody 20uL
|
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掲載カタログ情報
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