特徴
- 主な研究分野例:Cancer, Immunology
- 背景:This gene encodes a serum glycoprotein that forms a membrane attack complex together with complement components C5b, C6, C8, and C9 as part of the terminal complement pathway of the innate immune system. The protein encoded by this gene contains a cholesterol-dependent cytolysin/membrane attack complex/perforin-like (CDC/MACPF) domain and belongs to a large family of structurally related molecules that form pores involved in host immunity and bacterial pathogenesis. This protein initiates membrane attack complex formation by binding the C5b-C6 subcomplex and inserts into the phospholipid bilayer, serving as a membrane anchor. Mutations in this gene are associated with a rare disorder called C7 deficiency.C7 (Complement C7) is a Protein Coding gene. Diseases associated with C7 include C7 Deficiency and Immunodeficiency Due To A Late Component Of Complement Deficiency. Among its related pathways are Complement Pathway and Innate Immune System. An important paralog of this gene is C6.
仕様
- サイズ:120uL
- 抗体タイプ:Polyclonal Antibody
- アプリケーション:WB,ELISA
- 交差性:Human
- 宿主:Rabbit
- アイソタイプ:IgG
- 濃度:0.6 mg/mL
- 抗原:Fusion protein of human C7
- 緩衝液:PBS with 0.05% NaN3 and 40% Glycerol,pH7.4
- 精製方法:Antigen affinity purification
- 希釈倍率:WB 1:500-1:2000, ELISA 1:5000-1:10000
- 標識:Unconjugated
- クローナリティ:Polyclonal
- メーカーマニュアルリンク:https://www.elabscience.com/viewpdf-270902-Elabscience-E-AB-52507.pdf
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- 【試薬に関するお問合せ】
- アズワン株式会社 試薬・プロセス材料グループ
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商品のバリエーション (サイズ違い・スペック違い・オプション品など)
| 商品イメージ | アズワン品番 商品名 |
|---|---|
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89-7927-27
C7 Polyclonal Antibody 60uL
|
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89-7927-29
C7 Polyclonal Antibody 200uL
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89-7927-28
C7 Polyclonal Antibody 120uL
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89-7927-26
C7 Polyclonal Antibody 20uL
|
よくあるご質問(FAQ)
掲載カタログ情報
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