89-7923-79　ALKBH8 Polyclonal Antibody 60uL　E-AB-52350

特徴

• 主な研究分野例：Cancer, Epigenetics and Nuclear Signaling
• 背景：ALKBH8 (alkylated DNA repair protein AlkB homolog 8) is a 664 amino acid protein that is encoded by a gene located on chromosome 11. ALKBH8 contains one RRM (RNA recognition motif) domain and belongs to the AlkB family of proteins. ALKBH8 is one of many homologs of the Escherichia coli protein AlkB. AlkB functions to protect DNA and RNA against damage from environmental methylating compounds by directly reversing 1-methyladenine (1-meA) and 3-methylcytosine (3-meC) cytotoxic alkylation lesions in DNA and RNA. The enzyme acts by oxidative demethylation, utilizing ferrous iron and alpha-ketoglutarate as cofactors, 2-oxoglutarate as a co-substrate and molecular oxygen as the oxidizing agent. Three isoforms exist for ALKBH8 due alternative splicing of the gene.

仕様

• サイズ：60uL
• 抗体タイプ：Polyclonal Antibody
• アプリケーション：WB,IHC,ELISA
• 交差性：Human
• 宿主：Rabbit
• アイソタイプ：IgG
• 濃度：0.6 mg/mL
• 抗原：Full length fusion protein
• 緩衝液：PBS with 0.05% NaN3 and 40% Glycerol,pH7.4
• 精製方法：Antigen affinity purification
• 希釈倍率：WB 1:500-1:2000, IHC 1:25-1:100, ELISA 1:5000-1:10000
• 標識：Unconjugated
• クローナリティ：Polyclonal
• メーカーマニュアルリンク：https://www.elabscience.com/viewpdf-270745-Elabscience-E-AB-52350.pdf
• この商品は法規制を確認しておりません。（法規制によって販売できない場合もございます）

• 【試薬に関するお問合せ】
• アズワン株式会社 試薬・プロセス材料グループ
• TEL：06-6447-8641
• FAX：06-6447-8642
• E-mail：[email protected]