89-7919-13　MAPK8 Polyclonal Antibody 200uL　E-AB-52157

特徴

• 主な研究分野例：Cancer, Immunology, Signal Transduction
• 背景：MAPK8(Mitogen-activated protein kinase 8) is also named as JNK1,PRKM8,SAPK1,SAPK1C and belongs to the MAP kinase subfamily. MAPK8 is activated by dual phosphorylation at a Thr-Pro-Tyr motif during response to UV light. MAPK8 functions to phosphorylate c-Jun at N-terminal serine regulatory sites of Ser-63 and Ser-73,mapping within the transactivation domain. Phosphorylation of these sites in response to UV results in transcriptional activation of c-Jun. It has 4 isoforms produced by alternative splicing with the molecular weight of 46 kDa and 48 kDa. This protein can be phosphorylated and this antibody recognizes the 46 kDa and 55 kDa bands in western blot.

仕様

• サイズ：200uL
• 抗体タイプ：Polyclonal Antibody
• アプリケーション：WB,ELISA
• 交差性：Human, Mouse, Rat
• 宿主：Rabbit
• アイソタイプ：IgG
• 濃度：1.9 mg/mL
• 抗原：Fusion protein of human MAPK8
• 緩衝液：PBS with 0.05% NaN3 and 40% Glycerol,pH7.4
• 精製方法：Antigen affinity purification
• 希釈倍率：WB 1:1000-1:5000, ELISA 1:2000-1:10000
• 標識：Unconjugated
• クローナリティ：Polyclonal
• メーカーマニュアルリンク：https://www.elabscience.com/viewpdf-270552-Elabscience-E-AB-52157.pdf
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