89-7914-78 GRIA2 Polyclonal Antibody 60uL  E-AB-52034

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  • 主な研究分野例:Cancer, Neuroscience
  • 背景:Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. This gene product belongs to a family of glutamate receptors that are sensitive to alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate (AMPA), and function as ligand-activated cation channels. These channels are assembled from 4 related subunits, GRIA1-4. The subunit encoded by this gene (GRIA2) is subject to RNA editing (CAG->CGG; Q->R) within the second transmembrane domain, which is thought to render the channel impermeable to Ca(2+). Human and animal studies suggest that pre-mRNA editing is essential for brain function, and defective GRIA2 RNA editing at the Q/R site may be relevant to amyotrophic lateral sclerosis (ALS) etiology. Alternative splicing, resulting in transcript variants encoding different isoforms, (including the flip and flop isoforms that vary in their signal transduction properties), has been noted for this gene.


  • サイズ:60uL
  • 抗体タイプ:Polyclonal Antibody
  • アプリケーション:IHC,ELISA
  • 交差性:Human, Mouse, Rat
  • 宿主:Rabbit
  • アイソタイプ:IgG
  • 濃度:1.08 mg/mL
  • 抗原:Synthetic peptide of human GRIA2
  • 緩衝液:PBS with 0.05% NaN3 and 40% Glycerol,pH7.4
  • 精製方法:Antigen affinity purification
  • 希釈倍率:IHC 1:40-1:200, ELISA 1:5000-1:10000
  • 標識:Unconjugated
  • クローナリティ:Polyclonal
  • メーカーマニュアルリンク:https://www.elabscience.com/viewpdf-256039-Elabscience-E-AB-52034.pdf
  • この商品は法規制を確認しておりません。(法規制によって販売できない場合もございます)

アズワン品番 89-7914-78
型番 E-AB-52034
標準価格 39,000円(税抜)
入り数 1個
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