89-7913-79 Phospho-SMAD3 (Ser425) Monoclonal Antibody 200uL  E-AB-51043

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特徴

  • 主な研究分野例:Cancer, Epigenetics and Nuclear Signaling, Metabolism, Signal Transduction, Stem Cells
  • 背景:Receptor-regulated SMAD (R-SMAD) that is an intracellular signal transducer and transcriptional modulator activated by TGF-beta (transforming growth factor) and activin type 1 receptor kinases. Binds the TRE element in the promoter region of many genes that are regulated by TGF-beta and, on formation of the SMAD3/SMAD4 complex, activates transcription. Also can form a SMAD3/SMAD4/JUN/FOS complex at the AP-1/SMAD site to regulate TGF-beta-mediated transcription. Has an inhibitory effect on wound healing probably by modulating both growth and migration of primary keratinocytes and by altering the TGF-mediated chemotaxis of monocytes. This effect on wound healing appears to be hormone-sensitive. Regulator of chondrogenesis and osteogenesis and inhibits early healing of bone fractures. Positively regulates PDPK1 kinase activity by stimulating its dissociation from the 14-3-3 protein YWHAQ which acts as a negative regulator.

仕様

  • サイズ:200uL
  • 抗体タイプ:Phosphorylated antibody
  • アプリケーション:IHC-p
  • 交差性:Human,Mouse,Rat
  • 宿主:Mouse
  • アイソタイプ:IgG
  • 濃度:1 mg/mL
  • 抗原:Synthetic Peptide of Phospho-Smad3 (Ser425)
  • 緩衝液:PBS with 0.02% sodium azide and 50% glycerol pH 7.4.
  • 精製方法:Protein A purification
  • 希釈倍率:IHC 1:50-300
  • 標識:Unconjugated
  • クローナリティ:Monoclonal
  • この商品は法規制を確認しておりません。(法規制によって販売できない場合もございます)

アズワン品番 89-7913-79
型番 E-AB-51043
標準価格 73,000円(税抜)
WEB価格
入り数 1個
アズワン在庫 [?]
サプライヤ在庫 [?]
出荷予定日
数量

商品のバリエーション (サイズ違い・スペック違い・オプション品など)

アズワン品番 商品名 型番 入り数 標準価格
(税抜)
WEB価格
(税抜)
アズワン在庫[?]
[サプライヤ在庫]
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89-7913-78 Phospho-SMAD3 (Ser425) Monoclonal Antibody 120uL  E-AB-51043
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89-7913-79 Phospho-SMAD3 (Ser425) Monoclonal Antibody 200uL  E-AB-51043
E-AB-51043
  • 冷凍
1個 73,000円