89-7912-35　［取扱停止］CD22 Polyclonal Antibody 20uL　E-AB-40360

特徴

• 主な研究分野例：Cancer, Immunology, Stem Cells
• 背景：CD22,also known as Siglec-2 (sialic acid binding Ig-like lectin 2) or BL-CAM (B-lymphocyte cell adhesion molecule),is a 130-140 kDa,B-cell restricted,type I transmembrane glycoprotein belonging to the immunoglobulin gene superfamily. The expression of CD22 is developmentally regulated. It is expressed at low levels in the cytoplasm of pro-B and pre-B cells and present on the cell surface only at mature stages of B-cell differentiation. Cell surface expression is lost during terminal differentiation into plasma cell and after B-cell activation. CD22 is an inhibitory receptor for B-cell receptor (BCR) signalling,preferentially binds to alpha-2,6-linked sialic acid and mediates B-cell B-cell interactions. It plays a crucial role in activation and differentiation of the B-cell.

仕様

• サイズ：20uL
• 抗体タイプ：Polyclonal Antibody
• アプリケーション：IHC
• 交差性：Human
• 宿主：Rabbit
• アイソタイプ：IgG
• 濃度：1mg/mL
• 抗原：Recombinant Human B-cell receptor CD22 protein
• 緩衝液：PBS with 0.05% Proclin300 and 50% glycerol, pH7.3.
• 精製方法：Antigen Affinity Purification
• 希釈倍率：IHC 1:100-1:200
• 標識：Unconjugated
• クローナリティ：Polyclonal
• メーカーマニュアルリンク：https://www.elabscience.com/viewpdf-318205-Elabscience-E-AB-40360.pdf
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