89-7909-15　［取扱停止］Serpina1 Polyclonal Antibody 200uL　E-AB-40280

特徴

• 主な研究分野例：Cancer, Cardiovascular, Metabolism
• 背景：SERPINA1 is the gene for a protein called alpha-1-antitrypsin (AAT),which is a serine protease inhibitor whose targets include elastase,plasmin,thrombin,trypsin,chymotrypsin,and plasminogen activator. AAT is a glycoprotein synthesized primarily by hepatocytes,with smaller amountssynthesized by intestinal epithelial cells,neutrophils,pulmonary alveolar cells and macrophages. AAT is the most abundant,endogenous serine protease inhibitor in blood circulation and it has been implicated in regulating vital fluid phase biological events such as blood coagulation,fibrinolysis,complement activation,apoptosis,reproduction,tumor progression and inflammatory response. The primary function of AAT is thought to be the inactivation of neutrophil elastase and other endogenous serine proteases. Defects in SERPINA1 can cause emphysema or liver disease.

仕様

• サイズ：200uL
• 抗体タイプ：Polyclonal Antibody
• アプリケーション：IHC
• 交差性：Mouse,Rat
• 宿主：Rabbit
• アイソタイプ：IgG
• 濃度：1 mg/mL
• 抗原：Recombinant Rat Alpha-1-antiproteinase protein
• 緩衝液：PBS with 0.05% Proclin300 and 50% glycerol, pH7.4.
• 精製方法：Antigen Affinity Purification
• 希釈倍率：IHC 1:100-1:200
• 標識：Unconjugated
• クローナリティ：Polyclonal
• メーカーマニュアルリンク：https://www.elabscience.com/viewpdf-104561-Elabscience-E-AB-40280.pdf
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