89-7908-64　［取扱停止］PDGFB Polyclonal Antibody 60uL　E-AB-40267

特徴

• 主な研究分野例：Cancer, Cardiovascular, Metabolism, Developmental Biology, Signal Transduction
• 背景：The protein encoded by this gene is a member of the platelet-derived growth factor family. The four members of this family are mitogenic factors for cells of mesenchymal origin and are characterized by a motif of eight cysteines. This gene product can exist either as a homodimer (PDGF-BB) or as a heterodimer with the platelet-derived growth factor alpha polypeptide (PDGF-AB), where the dimers are connected by disulfide bonds. Mutations in this gene are associated with meningioma. Reciprocal translocations between chromosomes 22 and 7, at sites where this gene and that for COL1A1 are located, are associated with a particular type of skin tumor called dermatofibrosarcoma protuberans resulting from unregulated expression of growth factor. Two alternatively spliced transcript variants encoding different isoforms have been identified for this gene.

仕様

• サイズ：60uL
• 抗体タイプ：Polyclonal Antibody
• アプリケーション：IHC
• 交差性：Rat
• 宿主：Rabbit
• アイソタイプ：IgG
• 濃度：0.83 mg/mL
• 抗原：Recombinant Rat Platelet-derived growth factor subunit B protein
• 緩衝液：PBS with 0.05% Proclin300 and 50% glycerol, pH7.4.
• 精製方法：Antigen Affinity Purification
• 希釈倍率：IHC 1:100-1:200
• 標識：Unconjugated
• クローナリティ：Polyclonal
• メーカーマニュアルリンク：https://www.elabscience.com/viewpdf-104549-Elabscience-E-AB-40267.pdf
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