特徴
- 主な研究分野例：Cancer, Developmental Biology, Stem Cells
- 背景：IFITM3,also named as interferon-inducible protein 1-8U,belongs to the CD225 family. It is IFN-induced antiviral protein that mediates cellular innate immunity to at least three major human pathogens,namely influenza A H1N1 virus,West Nile virus (WNV),and dengue virus,by inhibiting the early steps of replication. IFITM3 is identified as interferon-induced cellular proteins that restrict infections by retroviruses and filoviruses and of influenza virus and flaviviruses,respectively. IFITM3,the most potent antiviral IFITM,was found to inhibit an uncharacterized early infectious event after VSV endocytosis,but before primary transcription of its viral genome. IFITM proteins are viral restriction factors that can inhibit infection mediated by the influenza A virus (IAV) hemagglutinin (HA) protein. They differentially restrict the entry of a broad range of enveloped viruses,and modulate cellular tropism independently of viral receptor expression. This antibody recognizes both IFITM2 and IFITM3.
仕様
- サイズ：20uL
- 抗体タイプ：Polyclonal Antibody
- アプリケーション：WB,IHC,IF
- 交差性：Human,Mouse,Rat
- 宿主：Rabbit
- アイソタイプ：IgG
- 濃度：1 mg/mL
- 抗原：Recombinant Rat Interferon-induced transmembrane protein 3 protein
- 緩衝液：PBS with 0.05% Proclin300 and 50% glycerol, pH7.4.
- 精製方法：Antigen Affinity Purification
- 希釈倍率：WB 1:1000-1:2000 IHC 1:50-1:200 IF 1:100-1:400
- 標識：Unconjugated
- クローナリティ：Polyclonal
- メーカーマニュアルリンク：https://www.elabscience.com/viewpdf-104545-Elabscience-E-AB-40263.pdf
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商品のバリエーション （サイズ違い・スペック違い・オプション品など）
| 商品イメージ | アズワン品番 商品名 |
|---|---|
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89-7908-48
IFITM3 Polyclonal Antibody 60uL
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89-7908-49
IFITM3 Polyclonal Antibody 120uL
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89-7908-47
IFITM3 Polyclonal Antibody 20uL
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89-7908-50
IFITM3 Polyclonal Antibody 200uL
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掲載カタログ情報
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