89-7908-45　［取扱停止］RUNX2 Polyclonal Antibody 120uL　E-AB-40262

特徴

• 主な研究分野例：Cancer, Epigenetics and Nuclear Signaling, Developmental Biology, Stem Cells
• 背景：This gene is a member of the RUNX family of transcription factors and encodes a nuclear protein with an Runt DNA-binding domain. This protein is essential for osteoblastic differentiation and skeletal morphogenesis and acts as a scaffold for nucleic acids and regulatory factors involved in skeletal gene expression. The protein can bind DNA both as a monomer or, with more affinity, as a subunit of a heterodimeric complex. Mutations in this gene have been associated with the bone development disorder cleidocranial dysplasia (CCD). Transcript variants that encode different protein isoforms result from the use of alternate promoters as well as alternate splicing.

仕様

• サイズ：120uL
• 抗体タイプ：Polyclonal Antibody
• アプリケーション：WB
• 交差性：Rat
• 宿主：Rabbit
• アイソタイプ：IgG
• 濃度：0.65 mg/mL
• 抗原：Recombinant Rat Runt-related transcription factor 2 protein
• 緩衝液：PBS with 0.05% Proclin300 and 50% glycerol, pH7.4.
• 精製方法：Antigen Affinity Purification
• 希釈倍率：WB 1:500-1:1000
• 標識：Unconjugated
• クローナリティ：Polyclonal
• メーカーマニュアルリンク：https://www.elabscience.com/viewpdf-104544-Elabscience-E-AB-40262.pdf
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