89-7906-95　［取扱停止］S100B Polyclonal Antibody 120uL　E-AB-40225

特徴

• 主な研究分野例：Cell Biology,Epigenetics and Nuclear Signaling,Stem Cells
• 背景：The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21; however, this gene is located at 21q22.3. This protein may function in Neurite extension, proliferation of melanoma cells, stimulation of Ca2+ fluxes, inhibition of PKC-mediated phosphorylation, astrocytosis and axonal proliferation, and inhibition of microtubule assembly. Chromosomal rearrangements and altered expression of this gene have been implicated in several neurological, neoplastic, and other types of diseases, including Alzheimer's disease, Down's syndrome, epilepsy, amyotrophic lateral sclerosis, melanoma, and type I diabetes.

仕様

• サイズ：120uL
• 抗体タイプ：Polyclonal Antibody
• アプリケーション：IHC
• 交差性：Rat
• 宿主：Rabbit
• アイソタイプ：IgG
• 濃度：2 mg/mL
• 抗原：Recombinant Rat Protein S100-B protien
• 緩衝液：PBS with 0.05% Proclin300 and 50% glycerol, pH7.4.
• 精製方法：Affinity purification
• 希釈倍率：IHC 1:50-1:200
• 標識：Unconjugated
• クローナリティ：Polyclonal
• メーカーマニュアルリンク：https://www.elabscience.com/viewpdf-50579-Elabscience-E-AB-40225.pdf
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