89-7906-68　［取扱停止］NR1H3 Polyclonal Antibody 200uL　E-AB-40217

特徴

• 主な研究分野例：Cardiovascular,Signal Transduction,Epigenetics and Nuclear Signaling,Signal Transduction,Cancer,Metabolism
• 背景：The protein encoded by this gene belongs to the NR1 subfamily of the nuclear receptor superfamily. The NR1 family members are key regulators of macrophage function, controlling transcriptional programs involved in lipid homeostasis and inflammation. This protein is highly expressed in visceral organs, including liver, kidney and intestine. It forms a heterodimer with retinoid X receptor (RXR), and regulates expression of target genes containing retinoid response elements. Studies in mice lacking this gene suggest that it may play an important role in the regulation of cholesterol homeostasis. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

仕様

• サイズ：200uL
• 抗体タイプ：Polyclonal Antibody
• アプリケーション：IHC
• 交差性：Rat
• 宿主：Rabbit
• アイソタイプ：IgG
• 濃度：2 mg/mL
• 抗原：Recombinant Rat Oxysterols receptor LXR-alpha protien
• 緩衝液：PBS with 0.05% Proclin300 and 50% glycerol, pH7.4.
• 精製方法：Affinity purification
• 希釈倍率：IHC 1:100-1:400
• 標識：Unconjugated
• クローナリティ：Polyclonal
• メーカーマニュアルリンク：https://www.elabscience.com/viewpdf-50571-Elabscience-E-AB-40217.pdf
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