89-7899-53　GFI1 Polyclonal Antibody 200uL　E-AB-19906

特徴

• 主な研究分野例：Cancer, Epigenetics and Nuclear Signaling
• 背景：This gene encodes a nuclear zinc finger protein that functions as a transcriptional repressor. This protein plays a role in diverse developmental contexts, including hematopoiesis and oncogenesis. It functions as part of a complex along with other cofactors to control histone modifications that lead to silencing of the target gene promoters. Mutations in this gene cause autosomal dominant severe congenital neutropenia, and also dominant nonimmune chronic idiopathic neutropenia of adults, which are heterogeneous hematopoietic disorders that cause predispositions to leukemias and infections. Multiple alternatively spliced variants, encoding the same protein, have been identified for this gene.

仕様

• サイズ：200uL
• 抗体タイプ：Polyclonal Antibody
• アプリケーション：IHC,ELISA
• 交差性：Human, Mouse, Rat
• 宿主：Rabbit
• アイソタイプ：IgG
• 濃度：1.86 mg/mL
• 抗原：Synthetic peptide of human GFI1
• 緩衝液：PBS with 0.05% NaN3 and 40% Glycerol,pH7.4
• 精製方法：Antigen affinity purification
• 希釈倍率：IHC 1:50-1:300, ELISA 1:5000-1:10000
• 標識：Unconjugated
• クローナリティ：Polyclonal
• メーカーマニュアルリンク：https://www.elabscience.com/viewpdf-255911-Elabscience-E-AB-19906.pdf
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