特徴
- 主な研究分野例:Cancer, Epigenetics and Nuclear Signaling
- 背景:This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbls class and, in addition to an F-box, contains at least six highly degenerated leucine-rich repeats. This family member plays a role in epigenetic silencing. It nucleates at CpG islands and specifically demethylates both mono- and di-methylated lysine-36 of histone H3. Alternative splicing results in multiple transcript variants.
仕様
- サイズ:200uL
- 抗体タイプ:Polyclonal Antibody
- アプリケーション:IHC,ELISA
- 交差性:Human, Mouse
- 宿主:Rabbit
- アイソタイプ:IgG
- 濃度:1.74 mg/mL
- 抗原:Synthetic peptide of human KDM2A
- 緩衝液:PBS with 0.05% NaN3 and 40% Glycerol,pH7.4
- 精製方法:Antigen affinity purification
- 希釈倍率:IHC 1:50-1:300, ELISA 1:5000-1:10000
- 標識:Unconjugated
- クローナリティ:Polyclonal
- メーカーマニュアルリンク:https://www.elabscience.com/viewpdf-255860-Elabscience-E-AB-19855.pdf
- この商品は法規制を確認しておりません。(法規制によって販売できない場合もございます)
- 【試薬に関するお問合せ】
- アズワン株式会社 試薬・プロセス材料グループ
- TEL:06-6447-8641
- FAX:06-6447-8642
- E-mail:[email protected]
商品のバリエーション (サイズ違い・スペック違い・オプション品など)
| 商品イメージ | アズワン品番 商品名 |
|---|---|
|
89-7897-62
KDM2A Polyclonal Antibody 120uL
|
|
|
89-7897-60
KDM2A Polyclonal Antibody 20uL
|
|
|
89-7897-63
KDM2A Polyclonal Antibody 200uL
|
|
|
89-7897-61
KDM2A Polyclonal Antibody 60uL
|
よくあるご質問(FAQ)
掲載カタログ情報
| 掲載カタログ名 | 掲載ページ |
|---|





