特徴
- 主な研究分野例:Cancer, Epigenetics and Nuclear Signaling
- 背景:The nucleosome, made up of four core histone proteins (H2A, H2B, H3, and H4), is the primary building block of chromatin. Originally thought to function as a static scaffold for DNA packaging, histones have now been shown to be dynamic proteins, undergoing multiple types of post-translational modifications, including acetylation, phosphorylation, methylation, and ubiquitination , acetylation of specific lysine residues creates docking sites that facilitate recruitment of many transcription and chromatin regulatory proteins that contain a bromodomain, which binds to acetylated lysine residues . Histone H2B is rapidly phosphorylated at irradiation-induced DNA damage foci in mouse embryonic fibroblasts .
仕様
- サイズ:120uL
- 抗体タイプ:Polyclonal Antibody
- アプリケーション:WB,IHC,ELISA
- 交差性:Human, Mouse, Rat
- 宿主:Rabbit
- アイソタイプ:IgG
- 濃度:1.98 mg/mL
- 抗原:Synthetic peptide of human HIST1H2BA
- 緩衝液:PBS with 0.05% NaN3 and 40% Glycerol,pH7.4
- 精製方法:Antigen affinity purification
- 希釈倍率:WB 1:500-1:2000, IHC 1:50-1:300, ELISA 1:5000-1:10000
- 標識:Unconjugated
- クローナリティ:Polyclonal
- メーカーマニュアルリンク:https://www.elabscience.com/viewpdf-255789-Elabscience-E-AB-19784.pdf
- この商品は法規制を確認しておりません。(法規制によって販売できない場合もございます)
- 【試薬に関するお問合せ】
- アズワン株式会社 試薬・プロセス材料グループ
- TEL:06-6447-8641
- FAX:06-6447-8642
- E-mail:[email protected]
商品のバリエーション (サイズ違い・スペック違い・オプション品など)
| 商品イメージ | アズワン品番 商品名 |
|---|---|
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89-7895-26
HIST1H2BA Polyclonal Antibody 20uL
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89-7895-28
HIST1H2BA Polyclonal Antibody 120uL
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89-7895-27
HIST1H2BA Polyclonal Antibody 60uL
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89-7895-29
HIST1H2BA Polyclonal Antibody 200uL
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よくあるご質問(FAQ)
掲載カタログ情報
| 掲載カタログ名 | 掲載ページ |
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