89-7856-13　ZNF354A Polyclonal Antibody 120uL　E-AB-18464

特徴

• 主な研究分野例：Epigenetics and Nuclear Signaling, Neuroscience
• 背景：ZNF354A, also called EZNF, KID-1 or TCF17, belongs to the Krüppel C2H2-type zinc-finger family of proteins that contain KRAB domains and act as transcriptional regulators. Expressed primarily in the adult kidney, ZNF354A is a transcriptional repressor that plays a role in late renal development and is suppressed after renal ischemia. The N-terminus of ZNF354A contains the KRAB domain which confers transcriptional repressor activity, while the C-terminus contains multiple Cys2His2-zinc fingers. ZNF354A is located in the nucleolus and is thought to specifically influence development of the proximal tubule by shutting off dispensable or inhibitory genes. Reduced ZNF354A expression prevents proper cell differentiation and may, therefore, be implicated in renal carcinoma.

仕様

• サイズ：120uL
• 抗体タイプ：Polyclonal Antibody
• アプリケーション：IHC,ELISA
• 交差性：Human, Mouse, Rat
• 宿主：Rabbit
• アイソタイプ：IgG
• 濃度：0.5 mg/mL
• 抗原：Fusion protein of human ZNF354A
• 緩衝液：PBS with 0.05% NaN3 and 40% Glycerol,pH7.4
• 精製方法：Antigen affinity purification
• 希釈倍率：IHC 1:30-1:150, ELISA 1:5000-1:10000
• 標識：Unconjugated
• クローナリティ：Polyclonal
• メーカーマニュアルリンク：https://www.elabscience.com/viewpdf-254469-Elabscience-E-AB-18464.pdf
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