特徴
- 主な研究分野例：Epigenetics and Nuclear Signaling
- 背景：Zinc-finger proteins contain DNA-binding domains and have a wide variety of functions, most of which encompass some form of transcriptional activation or repression. The majority of zinc-finger proteins contain a Krüppel-type DNA binding domain and a KRAB domain, which is thought to interact with KAP1, thereby recruiting histone modifying proteins. As a member of the krueppel C2H2-type zinc-finger protein family, ZNF486 (Zinc finger protein 486), also known as KRAB domain only protein 2, is a 216 amino acid nuclear protein that contains one KRAB domain and two C2H2-type zinc fingers. The gene encoding ZNF486 maps to human chromosome 19, which consists of over 63 million bases, houses approximately 1,400 genes and is recognized for having the greatest gene density of the human chromosomes. May be involved in transcriptional regulation.
仕様
- サイズ：20uL
- 抗体タイプ：Polyclonal Antibody
- アプリケーション：IHC,ELISA
- 交差性：Human
- 宿主：Rabbit
- アイソタイプ：IgG
- 濃度：0.9 mg/mL
- 抗原：Fusion protein of human ZNF486
- 緩衝液：PBS with 0.05% NaN3 and 40% Glycerol,pH7.4
- 精製方法：Antigen affinity purification
- 希釈倍率：IHC 1:40-1:250, ELISA 1:5000-1:10000
- 標識：Unconjugated
- クローナリティ：Polyclonal
- メーカーマニュアルリンク：https://www.elabscience.com/viewpdf-254367-Elabscience-E-AB-18362.pdf
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商品のバリエーション （サイズ違い・スペック違い・オプション品など）
| 商品イメージ | アズワン品番 商品名 |
|---|---|
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89-7854-34
ZNF486 Polyclonal Antibody 60uL
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89-7854-33
ZNF486 Polyclonal Antibody 20uL
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89-7854-35
ZNF486 Polyclonal Antibody 120uL
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89-7854-36
ZNF486 Polyclonal Antibody 200uL
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