89-7852-76　TBP Polyclonal Antibody 60uL　E-AB-18293

特徴

• 主な研究分野例：Cancer, Epigenetics and Nuclear Signaling
• 背景：The TATA binding protein (TBP) is a transcription factor that binds specifically to a DNA sequence TATA box. This DNA sequence is found about 25-30 base pairs upstream of the transcription start site in some eukaryotic gene promoters. TBP,along with a variety of TBP-associated factors,make up the TFIID,a general transcription factor that in turn makes up part of the RNA polymerase II preinitiation complex. As one of the few proteins in the preinitation complex that binds DNA in a sequence-specific manner,it helps position RNA polymerase II over the transcription start site of the gene. However,it is estimated that only 10-20% of human promoters have TATA boxes. Therefore,TBP is probably not the only protein involved in positioning RNA polymerase II. This antibody detects human TBP (~40 kDa) and mouse/rat Tbp (~35 kDa).

仕様

• サイズ：60uL
• 抗体タイプ：Polyclonal Antibody
• アプリケーション：WB,ELISA
• 交差性：Human
• 宿主：Rabbit
• アイソタイプ：IgG
• 濃度：0.8 mg/mL
• 抗原：Full length fusion protein
• 緩衝液：PBS with 0.05% NaN3 and 40% Glycerol,pH7.4
• 精製方法：Antigen affinity purification
• 希釈倍率：WB 1:500-1:2000, ELISA 1:5000-1:10000
• 標識：Unconjugated
• クローナリティ：Polyclonal
• メーカーマニュアルリンク：https://www.elabscience.com/viewpdf-254298-Elabscience-E-AB-18293.pdf
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