89-7834-77 Recombinant Rat SCF/c-Kit Ligand Protein (Human Cells, His Tag) 10ug PKSR030459
[Elabscience]
特徴
- 背景：SCF/C-kit ligand is the ligand of the tyrosine-kinase receptor encoded by the KIT locus. Plays an essential role in the regulation of cell survival and proliferation, hematopoiesis, stem cell maintenance, gametogenesis, mast cell development, migration and function, and in melanogenesis. KITLG/SCF binding can activate several signaling pathways. Promotes phosphorylation of PIK3R1, the regulatory subunit of phosphatidylinositol 3-kinase, and subsequent activation of the kinase AKT1. In phase I/II clinical studies administration of the combination of SCF and G-CSF resulted in a two- to threefold increase in cells that express the CD34 antigen compared with G-CSF alone.
仕様
- サイズ：10ug
- 種由来：Rat
- 発現宿主：Human Cells
- 純度：> 95% as determined by reducing SDS-PAGE.
- エンドトキシン濃度：< 1.0 EU per μg as determined by the LAL method.
- アクセッションＮｏ．：P21581
- タグ種類：C-His
- アミノ酸配列：Gln26-Ala189
- 遺伝子構造：Recombinant Rat SCF is produced by our Mammalian expression system and the target gene encoding Gln26-Ala189 is expressed with a 6His tag at the C-terminus.
- 別名（遺伝子名）：FPH2; KIT ligand; Kitl; KITLG; KL-1; Mast cell growth factor; MGF; MGFSHEP7; SCF; SFc-Kit ligand; SLF; steel factor; Stem Cell Factor; c-kit Ligand
- 分子量：19.4 kDa
- 組成：Lyophilized from a 0.2 μm filtered solution of PBS,pH 7.4.
- 保存条件：Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
- メーカーマニュアルリンク：https://www.elabscience.com/viewpdf-229842-Elabscience-PKSR030459.pdf
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商品のバリエーション （サイズ違い・スペック違い・オプション品など）
| 商品イメージ | アズワン品番 商品名 |
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89-7834-78
Recombinant Rat SCF/c-Kit Ligand Protein (Human Cells, His Tag) 50ug
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89-7834-77
Recombinant Rat SCF/c-Kit Ligand Protein (Human Cells, His Tag) 10ug
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