特徴
- 背景：T-lymphocyte activation antigen CD86 (B7-2) is a glycosylated protein in the B7 family. B7 family members are transmembrane cell surface molecules that play important roles in immune activation and the maintenance of immune tolerance. It is highly expressed on activated antigen presenting cells. CD86 involved in the costimulatory signal essential for T-lymphocyte proliferation and interleukin-2 production, by binding CD28 or CTLA-4. It may play a critical role in the early events of T-cell activation and costimulation of naive T-cells, such as deciding between immunity and anergy that is made by T-cells within 24 hours after activation. It is expressed by activated B-lymphocytes and monocytes and promoted by MARCH8 and results in endocytosis and lysosomal degradation.
仕様
- サイズ：10ug
- 種由来：Rat
- 発現宿主：Human cells
- 純度：> 95 % as determined by SDS-PAGE
- エンドトキシン濃度：<1.0 EU per μg as determined by LAL test.
- アクセッションＮｏ．：O35531
- タグ種類：C-6His
- アミノ酸配列：Vla29-Lys247
- 遺伝子構造：Recombinant Rat T-lymphocyte Activation Antigen CD86 is produced by our Mammalian expression system and the target gene encoding Vla29-Lys247 is expressed with a 6His tag at the C-terminus.
- 別名（遺伝子名）：T-lymphocyte activation antigen CD86; Activation B7-2 antigen; CD86;B7-2;B7.2;B70;CD28LG2;LAB72
- 分子量：25.9 kDa
- 組成：Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4.
- 保存条件：Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
- メーカーマニュアルリンク：https://www.elabscience.com/viewpdf-137345-Elabscience-PKSR030456.pdf
- この商品は法規制を確認しておりません。（法規制によって販売できない場合もございます）
- 【試薬に関するお問合せ】
- アズワン株式会社 試薬・プロセス材料グループ
- TEL：06-6447-8641
- FAX：06-6447-8642
- E-mail：[email protected]
商品のバリエーション （サイズ違い・スペック違い・オプション品など）
| 商品イメージ | アズワン品番 商品名 |
|---|---|
|
89-7834-71
Recombinant Rat CD86/B7-2 Protein (His Tag) 10ug
|
|
|
89-7834-72
Recombinant Rat CD86/B7-2 Protein (His Tag) 50ug
|
よくあるご質問（FAQ）
掲載カタログ情報
| 掲載カタログ名 | 掲載ページ |
|---|