89-7834-69 Recombinant Rat HER2/ErbB2 Protein (aa 67-323, His Tag) 10ug PKSR030455
[Elabscience]
特徴
- 背景：ERBB2 belongs to the protein kinase superfamily, Tyr protein kinase family and EGF receptor subfamily. It contains a protein kinase domain. ERBB2 is widely expressed in epithelial cells, and amplification and/or overexpression of ErbB2 has been reported associated with malignancy and a poor prognosis in numerous carcinomas, including breast, prostate and ovarian cancers. Rat ERBB2 is an essential component of a neuregulin-receptor complex, although neuregulins do not interact with it alone. ErbB2 mediates signalling pathways which involve mitogen-activated protein kinase and phosphatidylinositol-3 kinase, this receptor plays a key role in development, cell proliferation and differentiation.
仕様
- サイズ：10ug
- 種由来：Rat
- 発現宿主：E.coli
- 純度：> 95 % as determined by SDS-PAGE
- エンドトキシン濃度：<1.0 EU per μg as determined by LAL test.
- アクセッションＮｏ．：P06494
- タグ種類：C-6His
- アミノ酸配列：Ala67-Val323
- 遺伝子構造：Recombinant Rat Receptor tyrosine-protein kinase ErbB-2 is produced by our E.coli expression system and the target gene encoding Ala67-Val323 is expressed with a 6His tag at the C-terminus.
- 別名（遺伝子名）：Receptor tyrosine-protein kinase erbB-2; Epidermal growth factor receptor-related protein; Proto-oncogene Neu; Proto-oncogene c-ErbB-2; p185erbB2; p185neu; CD340; ERBB2;ENV;ENVW;ERVWE1;HER-2;HER-2/neu;HER2;HERV-7q;HERV-W-ENV;HERV7Q;HERVW;HERVWENV;MLN 19;MLN19
- 分子量：29.3 kDa
- 組成：Lyophilized from a 0.2 μm filtered solution of 20mM Tris,150mM NaCl, 4M Urea, pH 8.0.
- 保存条件：Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
- メーカーマニュアルリンク：https://www.elabscience.com/viewpdf-137344-Elabscience-PKSR030455.pdf
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商品のバリエーション （サイズ違い・スペック違い・オプション品など）
| 商品イメージ | アズワン品番 商品名 |
|---|---|
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89-7834-70
Recombinant Rat HER2/ErbB2 Protein (aa 67-323, His Tag) 50ug
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89-7834-69
Recombinant Rat HER2/ErbB2 Protein (aa 67-323, His Tag) 10ug
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