特徴
- 背景：Cluster of Differentiation 80, also called B7-1, is a member of cell surface immunoglobulin superfamily which plays key, yet distinct roles in the activation of T cells. B7-1/CD80 and B7-2/CD86, together with their receptors CD28 and CTLA4, constitute one of the dominant co-stimulatory pathways that regulate T- and B- cell responses. CD80 is mostly expressed on the surface of antigen-presenting cells including activated B cells, macrophages and dendritic cells. Although both CTLA-4 and CD28 can bind to the same ligands, CTLA-4 binds to B7-1 and B7-2 with a 20-100 fold higher affinity than CD28 and is involved in the down-regulation of the immune response.
仕様
- サイズ：10ug
- 種由来：Rat
- 発現宿主：Human cells
- 純度：> 95 % as determined by SDS-PAGE
- エンドトキシン濃度：<1.0 EU per μg as determined by LAL test.
- アクセッションＮｏ．：O35187
- タグ種類：C-6His
- アミノ酸配列：Vla30-Gln248
- 遺伝子構造：Recombinant Rat T-lymphocyte Activation Antigen CD81 is produced by our Mammalian expression system and the target gene encoding Vla30-Gln248 is expressed with a 6His tag at the C-terminus.
- 別名（遺伝子名）：T-lymphocyte activation antigen CD80; Activation B7-1 antigen; B7; CD80
- 分子量：25.7 kDa
- 組成：Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4.
- 保存条件：Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
- メーカーマニュアルリンク：https://www.elabscience.com/viewpdf-107027-Elabscience-PKSR030453.pdf
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商品のバリエーション （サイズ違い・スペック違い・オプション品など）
| 商品イメージ | アズワン品番 商品名 |
|---|---|
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89-7834-65
Recombinant Rat CD80/B7-1 Protein (His Tag) 10ug
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89-7834-66
Recombinant Rat CD80/B7-1 Protein (His Tag) 50ug
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