特徴
- 背景：Immunoglobulin G (IgG) is a type of antibody composed of four peptide chains—two identical heavy chains and two identical light chains arranged in a Y-shape typical of antibody monomers.There are four IgG subclasses (IgG1, 2, 3, and 4) in humans, named in order of their abundance in serum. The IgG2a isotype was able to interact very efficiently with FcgammaR, and share approximately 64-78% amino acid sequence identity with IgG1 and IgG2b in the heavy chain constant region domains, CH1, CH2 and CH3, which cause the diffrence in the interaction with complement, NK and mast cells, induction or inhibition by specific cytokines, and ability to cross the placenta.
仕様
- サイズ：10ug
- 種由来：Rat
- 発現宿主：Human cells
- 純度：> 95 % as determined by SDS-PAGE
- エンドトキシン濃度：<1.0 EU per μg as determined by LAL test.
- アクセッションＮｏ．：P20760
- アミノ酸配列：Val98-Lys322
- 遺伝子構造：Recombinant Rat Immunoglobulin G2A Fc is produced by our Mammalian expression system and the target gene encoding Val98-Lys322 is expressed.
- 別名（遺伝子名）：Ig gamma-2A chain C region; Igg-2a
- 分子量：35.2 kDa
- 組成：Lyophilized from a 0.2 μm filtered solution of 20mM Tris, pH 8.5.
- 保存条件：Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
- メーカーマニュアルリンク：https://www.elabscience.com/viewpdf-107024-Elabscience-PKSR030448.pdf
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商品のバリエーション （サイズ違い・スペック違い・オプション品など）
| 商品イメージ | アズワン品番 商品名 |
|---|---|
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89-7834-58
Recombinant Rat IgG2A Fc/Igg-2a Protein 50ug
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89-7834-57
Recombinant Rat IgG2A Fc/Igg-2a Protein 10ug
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