特徴
- 背景:Granulocyte-Macrophage Colony Stimulating Factor (GM-CSF) was initially characterized as a growth factorthat can support the in vitro colony formation of granulocyte-macrophage progenitors. It is produced by anumber of different cell types (including activated T cells, B cells, macrophages, mast cells, endothelial cellsand fibroblasts) in response to cytokine of immune and inflammatory stimuli. Besides granulocyte-macrophageprogenitors, GM-CSF is also a growth factor for erythroid, megakaryocyte and eosinophil progenitors. Onmature hematopoietic, monocytes/ macrophages and eosinophils. GM-CSF has a functional role on nonhematopoitic cells. It can induce human endothelial cells to migrate and proliferate. Additionally, GM-CSF canalso stimulate the proliferation of a number of tumor cell lines, including osteogenic sarcoma, carcinoma andadenocarcinoma cell lines.
仕様
- サイズ:10ug
- 種由来:Rat
- 発現宿主:Human cells
- 純度:> 95 % as determined by SDS-PAGE
- エンドトキシン濃度:<1.0 EU per μg as determined by LAL test.
- アクセッションNo.:P48750
- タグ種類:C-6His
- アミノ酸配列:Ala18-Lys144
- 遺伝子構造:Recombinant Rat Granulocyte-Macrophage Colony-Stimulating Factor is produced by our Mammalian expression system and the target gene encoding Ala18-Lys144 is expressed with a 6His tag at the C-terminus.
- 別名(遺伝子名):Granulocyte-Macrophage Colony-Stimulating Factor; GM-CSF; Colony-Stimulating Factor; CSF;Molgramostin; Sargramostim; CSF2; GMCSF
- 分子量:15.6 kDa
- 組成:Lyophilized from a 0.2 μm filtered solution of PBS pH7.4.
- 保存条件:Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
- メーカーマニュアルリンク:https://www.elabscience.com/viewpdf-106940-Elabscience-PKSR030447.pdf
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商品のバリエーション (サイズ違い・スペック違い・オプション品など)
| 商品イメージ | アズワン品番 商品名 |
|---|---|
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89-7834-56
Recombinant Rat GM-CSF/CSF2 Protein (His Tag) 50ug
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89-7834-55
Recombinant Rat GM-CSF/CSF2 Protein (His Tag) 10ug
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