89-7834-35 Recombinant Rat IL-6/Interleukin-6 Protein (Active) 20ug PKSR030420
[Elabscience]
特徴
- 背景：Interleukin-6 (IL-6) is a multifunctional α-helical cytokine that regulates cell growth and differentiation of various tissues, which is known particularly for its role in the immune response and acute phase reactions. IL-6 protein is secreted by a variety of cell types including T cells and macrophages as phosphorylated and variably glycosylated molecule. It exerts actions through the its heterodimeric receptor composed of IL-6R that lacks the tyrosine/kinase domain and binds IL-6 with low affinity, and ubiquitously expressed glycoprotein 130 (gp130) that binds the IL-6. IL-6R complex with high affinity and thus transduces signals. IL-6 is also involved in hematopoiesis, bone metabolism, and cancer progression, and has been defined an essential role in directing transition from innate to acquired immunity.Immune Checkpoint Immunotherapy Cancer Immunotherapy Targeted Therapy
仕様
- サイズ：20ug
- 種由来：Rat
- 発現宿主：E. coli
- 純度：> 90 % as determined by SDS-PAGE
- エンドトキシン濃度：Please contact us for more information.
- アクセッションＮｏ．：NP_036721.1
- アミノ酸配列：Phe25-Thr211
- 遺伝子構造：A DNA sequence encoding the rat IL6 (Phe25-Thr211) was expressed and purified with an initial Met.
- 活性：Measured in a cell proliferation assay using T1165 mouse plasmacytoma cells.The ED50 for this effect is typically 1-6 ng/ml.
- 別名（遺伝子名）：IL6
- 分子量：21.9 kDa
- 組成：Lyophilized from sterile 40% acetonitrile, 0.1% TFA
- 保存条件：Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
- メーカーマニュアルリンク：https://www.elabscience.com/viewpdf-106945-Elabscience-PKSR030420.pdf
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商品のバリエーション （サイズ違い・スペック違い・オプション品など）
| 商品イメージ | アズワン品番 商品名 |
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89-7834-35
Recombinant Rat IL-6/Interleukin-6 Protein (Active) 20ug
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89-7834-36
Recombinant Rat IL-6/Interleukin-6 Protein (Active) 100ug
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