89-7834-01 ［取扱停止］Recombinant Rat CNTFR/CNTFR-alpha Protein (His Tag)(Active) 50ug PKSR030401
[Elabscience]
特徴
- 背景：Ciliary neurotrophic factor(CNTF) is a member of the cytokine family. It is a polypeptide hormone that have functions in promoting neurotransmitter synthesis and neurite outgrowth in certain neuronal populations. It's actions appear to be restricted to the nervous system. Ciliary neurotrophic factor(CNTF) has biological effects through the activation of a multi-subunit receptor complex, consisting of an extracelluar CNTF binding subunit(CNTFα) and two transmembrane signal transduction proteins: glycoprotein gp130 and LIF receptor. CNTF is considered as a potent survival factor of neurons and oligodendrocytes and may be relevant in reducing tissue destruction during inflammatory attacks. CNTF is also a survival factor for neurons of the peripheral sensory sympathetic, and ciliary ganglia. It has been reported that CNTF could be an agent that has therapeutic potential and possibly induces differentiation of large multipolar ganglionic phenotype in a subset of progenitors.
仕様
- サイズ：50ug
- 種由来：Rat
- 発現宿主：Baculovirus-Insect Cells
- 純度：> 97 % as determined by SDS-PAGE
- エンドトキシン濃度：< 1.0 EU per μg of the protein as determined by the LAL method
- アクセッションＮｏ．：Q08406-1
- タグ種類：C-His
- アミノ酸配列：Met 1-Pro 346
- 遺伝子構造：A DNA sequence encoding the rat CNTFR (Q08406-1) (Met 1-Pro 346) was fused with a C-terminal polyhistidine tag.
- 活性：Measured by its binding ability in a functional ELISA. Immobilized Rat CTNFR at 10 μg/ml (100 μl/well) can bind biotinylated human CNTF with a linear ranger of 1.28-160 ng/ml.
- 別名（遺伝子名）：Cntfr
- 分子量：39.6 kDa
- 組成：Lyophilized from sterile 20mM Tris, 500mM NaCl, 10% gly, pH 8.0
- 保存条件：Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
- メーカーマニュアルリンク：https://www.elabscience.com/viewpdf-38473-Elabscience-PKSR030401.pdf
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商品のバリエーション （サイズ違い・スペック違い・オプション品など）
| 商品イメージ | アズワン品番 商品名 |
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89-7834-02
Recombinant Rat CNTFR/CNTFR-alpha Protein (His Tag)(Active) 100ug
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89-7834-01
Recombinant Rat CNTFR/CNTFR-alpha Protein (His Tag)(Active) 50ug
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