89-7833-30 ［取扱停止］Recombinant Rat EGFR/ErbB1 Protein (His Tag)(Active) 50ug PKSR030363
[Elabscience]
特徴
- 背景：As a member of the epidermal growth factor receptor (EGFR) family, EGFR protein is type I transmembrane glycoprotein that binds a subset of EGF family ligands including EGF, amphiregulin, TGF-α, betacellulin, etc. EGFR protein plays a crucial role in signaling pathway in the regulation of cell proliferation, survival and differentiation. Binding of a ligand induces EGFR protein homo- or heterodimerization, the subsequent tyrosine autophosphorylation and initiates various down stream pathways (MAPK, PI3K/PKB and STAT). In addition, EGFR signaling also has been shown to exert action on carcinogenesis and disease progression, and thus EGFR protein is proposed as a target for cancer therapy currently.Immune Checkpoint Immunotherapy Cancer Immunotherapy Targeted Therapy
仕様
- サイズ：50ug
- 種由来：Rat
- 発現宿主：HEK293 Cells
- 純度：> 98 % as determined by SDS-PAGE
- アクセッションＮｏ．：E7CXR8
- タグ種類：C-His
- アミノ酸配列：Met1-Ser646
- 遺伝子構造：A DNA sequence encoding the rat EGFR (E7CXR8) (Met1-Ser646) was expressed, fused with a polyhistidine tag at the C-terminus.
- 活性：1. Measured by its ability to bind recombinant human EGF-Fc in a functional ELISA.2. Measured by its ability to bind recombinant mouse EGF-Fc in a functional ELISA.
- 別名（遺伝子名）：EGFR
- 分子量：70.7 kDa
- 組成：Lyophilized from sterile PBS, pH 7.4
- 保存条件：Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
- メーカーマニュアルリンク：https://www.elabscience.com/viewpdf-107006-Elabscience-PKSR030363.pdf
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商品のバリエーション （サイズ違い・スペック違い・オプション品など）
| 商品イメージ | アズワン品番 商品名 |
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89-7833-30
Recombinant Rat EGFR/ErbB1 Protein (His Tag)(Active) 50ug
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89-7833-31
Recombinant Rat EGFR/ErbB1 Protein (His Tag)(Active) 100ug
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