89-7832-85 ［取扱停止］Recombinant Rat LTBR/TNFRSF3 Protein (Fc Tag) 50ug PKSR030341
[Elabscience]
特徴
- 背景：LTBR (lymphotoxin beta receptor (TNFR superfamily, member 3)) is a member of the tumor necrosis factor (TNF) family of receptors. Tumor necrosis factor receptor is a trimeric cytokine receptor that binds tumor necrosis factors. The receptor cooperates with an adaptor protein (such as TRADD, TRAF, RIP), which is important in determining the outcome of the response. LTBR is expressed on the surface of most cell types, including cells of epithelial and myeloid lineages, but not on T and B lymphocytes. LTBR specifically binds the lymphotoxin membrane form (a complex of lymphotoxin-alpha and lymphtoxin-beta). LTBR and its ligand play a role in the development and organization of lymphoid tissue and tranformed cells. Activation of this protein can trigger apoptosis. Not only does the LTBR help trigger apoptosis, it can lead to the release of the cytokine interleukin 8. Overexpression of LTBR in HEK293 cells increases IL-8 promoter activity and leads to IL-8 release. It is also essential for development and organization of the secondary lymphoid organs and chemokine release.
仕様
- サイズ：50ug
- 種由来：Rat
- 発現宿主：HEK293 Cells
- 純度：(9.8+79.7) % as determined by SDS-PAGE
- エンドトキシン濃度：< 1.0 EU per μg of the protein as determined by the LAL method
- アクセッションＮｏ．：Q5U2S8
- タグ種類：C-Fc
- アミノ酸配列：Met1-Ala218
- 遺伝子構造：A DNA sequence encoding the rat LTBR (Q5U2S8) (Met1-Ala218) was expressed with the Fc region of human IgG1 at the C-terminus.
- 別名（遺伝子名）：LTBR
- 分子量：48.5 kDa
- 組成：Lyophilized from sterile PBS, pH 7.4
- 保存条件：Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
- メーカーマニュアルリンク：https://www.elabscience.com/viewpdf-38434-Elabscience-PKSR030341.pdf
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| 商品イメージ | アズワン品番 商品名 |
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89-7832-85
Recombinant Rat LTBR/TNFRSF3 Protein (Fc Tag) 50ug
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89-7832-86
Recombinant Rat LTBR/TNFRSF3 Protein (Fc Tag) 100ug
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