89-7832-64 Recombinant Rat GITR/TNFRSF18 Protein (Fc Tag) 100ug PKSR030328
[Elabscience]
特徴
- 背景：GITR, also known as TNFRSF18(CD357), belongs to the tumor necrosis factor receptor (TNF-R) superfamily. It is the receptor for TNFSF18. GITR plays a key role in dominant immunological self-tolerance maintained by CD25(+)CD4(+) regulatory T cells. GITR may be involved in interactions between activated T-lymphocytes and endothelial cells and in the regulation of T-cell receptor-mediated cell death. GITR and its ligand are important costimulatory molecules in the pathogenesis of autoimmune diseases. It also mediates NF-kappa-B activation via the TRAF2/NIK pathway.Immune CheckpointImmune Checkpoint Detection: ELISA AntibodiesImmune Checkpoint Targets Co-stimulatory Immune Checkpoint Targets Immunotherapy Cancer Immunotherapy Targeted Therapy
仕様
- サイズ：100ug
- 種由来：Rat
- 発現宿主：HEK293 Cells
- 純度：> 95 % as determined by SDS-PAGE
- エンドトキシン濃度：< 1.0 EU per μg of the protein as determined by the LAL method
- アクセッションＮｏ．：Q5M835
- タグ種類：C-Fc
- アミノ酸配列：Met1-Lys121
- 遺伝子構造：A DNA sequence encoding the rat TNFRSF18 (Q5M835) (Met1-Lys121) was expressed, fused with the Fc region of human IgG1 at the C-terminus.
- 別名（遺伝子名）：TNFRSF18
- 分子量：37.7 kDa
- 組成：Lyophilized from sterile PBS, pH 7.4
- 保存条件：Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
- メーカーマニュアルリンク：https://www.elabscience.com/viewpdf-38425-Elabscience-PKSR030328.pdf
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| 商品イメージ | アズワン品番 商品名 |
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89-7832-64
Recombinant Rat GITR/TNFRSF18 Protein (Fc Tag) 100ug
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89-7832-63
Recombinant Rat GITR/TNFRSF18 Protein (Fc Tag) 50ug
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