89-7830-91 ［取扱停止］Recombinant Rat CD133/PROM1/Prominin 1 Protein (Fc Tag) 20ug PKSR030231
[Elabscience]
特徴
- 背景：CD133, also known as PROM1 and Prominin 1, is a pentaspan transmembrane glycoprotein which belongs to the prominin family. It localizes to membrane protrusions and is often expressed on adult stem cells. CD133 is known to play a role in maintaining stem cell properties by suppressing differentiation. CD133 binds cholesterol in cholesterol-containing plasma membrane microdomains. It is proposed to play a role in apical plasma membrane organization of epithelial cells. CD133 is also involved in regulation of MAPK and Akt signaling pathways. Mutations in PROM1 gene have been shown to result in retinitis pigmentosa and Stargardt disease. PROM1 gene is expressed from at least five alternative promoters that are expressed in a tissue-dependent manner. Expression of this gene is also associated with several types of cancer.
仕様
- サイズ：20ug
- 種由来：Rat
- 発現宿主：HEK293 Cells
- 純度：(79.2+14.5) % as determined by SDS-PAGE
- エンドトキシン濃度：< 1.0 EU per μg of the protein as determined by the LAL method
- アクセッションＮｏ．：NP_001103607.1
- タグ種類：N-Fc
- アミノ酸配列：Asn171-Tyr424
- 遺伝子構造：A DNA sequence encoding the rat PROM1 (NP_001103607.1) (Asn171-Tyr424) was with the Fc region of mouse IgG1 at the N-terminus.
- 別名（遺伝子名）：PROM1
- 分子量：55.1 kDa
- 組成：Lyophilized from sterile PBS, pH 7.4
- 保存条件：Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
- メーカーマニュアルリンク：https://www.elabscience.com/viewpdf-106975-Elabscience-PKSR030231.pdf
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商品のバリエーション （サイズ違い・スペック違い・オプション品など）
| 商品イメージ | アズワン品番 商品名 |
|---|---|
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89-7830-92
Recombinant Rat CD133/PROM1/Prominin 1 Protein (Fc Tag) 100ug
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89-7830-91
Recombinant Rat CD133/PROM1/Prominin 1 Protein (Fc Tag) 20ug
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