89-7830-57 ［取扱停止］Recombinant Rat c-MPL/CD110/TPOR Protein (His Tag) 50ug PKSR030214
[Elabscience]
特徴
- 背景：CD110, also known as c-MPL, is a 635 amino acid transmembrane domain, with two extracellular cytokine receptor domains and two intracellular cytokine receptor box motifs. It is expressed at a low level in a large number of cells of hematopoietic origin. C-MPL is homologous with members of the hematopoietic receptor superfamily. Presence of anti-sense oligodeoxynucleotides of c-mpl inhibited megakaryocyte colony formation. Thrombopoietin is the ligand for c-mpl. It was shown to be the major regulator of megakaryocytopoiesis and platelet formation. Defects in c-MPL are a cause of congenital amegakaryocytic thrombocytopeniawhich is a disease characterized by isolated thrombocytopenia and megakaryocytopenia with no physical anomalies. Defects in c-MPL also cause thrombocythemia type 2 and myelofibrosis with myeloid metaplasia.
仕様
- サイズ：50ug
- 種由来：Rat
- 発現宿主：Baculovirus-Insect Cells
- 純度：> 90 % as determined by SDS-PAGE
- エンドトキシン濃度：< 1.0 EU per μg of the protein as determined by the LAL method
- タグ種類：C-His
- アミノ酸配列：Met1-Ala500
- 遺伝子構造：A DNA sequence encoding the mature form of rat MPL (Met1-Ala500) was expressed with a polyhistide tag at the C-terminus.
- 別名（遺伝子名）：MPL
- 分子量：55.1 kDa
- 組成：Lyophilized from sterile 20mM Tris, 500mM NaCl, 3mM DTT, 10%glycerol, pH 7.5
- 保存条件：Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
- メーカーマニュアルリンク：https://www.elabscience.com/viewpdf-106971-Elabscience-PKSR030214.pdf
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商品のバリエーション （サイズ違い・スペック違い・オプション品など）
| 商品イメージ | アズワン品番 商品名 |
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89-7830-57
Recombinant Rat c-MPL/CD110/TPOR Protein (His Tag) 50ug
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89-7830-58
Recombinant Rat c-MPL/CD110/TPOR Protein (His Tag) 100ug
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