89-7830-35 ［取扱停止］Recombinant Rat LAG3/CD223 Protein (His Tag) 50ug PKSR030201
[Elabscience]
特徴
- 背景：LAG3, also known as CD223 and Lymphocyte activation gene 3, belongs to immunoglobulin (Ig) superfamily. LAG3 contains 4 extracellular Ig-like domains. The LAG3 gene contains 8 exons. It is selectively expressed in activated T and NK cells. LAG3 has a negative regulatory function in T cells. It also acts as as a new marker of T cell induced B cell activation. As a soluble molecule, LAG3 activates antigen-presenting cells through MHC class II signalling, leading to increased antigen-specific T-cell responses in vivo.Immune CheckpointImmune Checkpoint Targets Co-inhibitory Immune Checkpoint Targets Immunotherapy Cancer Immunotherapy Targeted Therapy
仕様
- サイズ：50ug
- 種由来：Rat
- 発現宿主：HEK293 Cells
- 純度：> 90 % as determined by SDS-PAGE
- エンドトキシン濃度：< 1.0 EU per μg of the protein as determined by the LAL method
- アクセッションＮｏ．：Q5BK54
- タグ種類：C-His
- アミノ酸配列：Met1-Leu442
- 遺伝子構造：A DNA sequence encoding the rat LAG3 (Q5BK54)(Met1-Leu442) was expressed with a polyhistidine tag at the C-terminus.
- 別名（遺伝子名）：LAG3
- 分子量：47.1 kDa
- 組成：Lyophilized from sterile 20 mM NaAc, 500 mM NaCl, 10 % Glycerol, 0.02 % tween 20, pH 5.5
- 保存条件：Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
- メーカーマニュアルリンク：https://www.elabscience.com/viewpdf-106969-Elabscience-PKSR030201.pdf
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商品のバリエーション （サイズ違い・スペック違い・オプション品など）
| 商品イメージ | アズワン品番 商品名 |
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89-7830-36
Recombinant Rat LAG3/CD223 Protein (His Tag) 100ug
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89-7830-35
Recombinant Rat LAG3/CD223 Protein (His Tag) 50ug
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